Regression assumptions
There are a few assumptions that underlie regression analysis:
If the assumptions are not violated, then the Gauss-Markov theorem indicates that the OLS estimates (e.g. eqns 13 and 14) are optimal in the sense of being unbiased and having minimum variance. If one or more of the assumptions are violated, then estimated regression coefficients may be biased (i.e. they may be systematically in error), and not minimum variance (i.e. there may be more uncertainty in the coefficients than is apparent from the results).
Consequences of assumption violations
If the assumptions are violated, then there may be two consequences--the estimated coefficients may be biased (i.e. systematically wrong), and they may longer have minimum variance (i.e. their uncertainty increases).
Testing for assumption violations with diagnostic analyses
There are several ways to test whether the assumptions that underlie regression analysis have been violated. As might be expected, these include analytical methods, in which the values of particular test statistics are computed and compared with appropriate reference distributions, and graphical methods, which are often easier to implement (and just as informative).